An overview of bone diseases

How severely movement is impaired depends on the type and severity of the problem.

An overview of bone diseases

Print About Osteomalacia and Rickets Osteomalacia is a disorder marked by inadequate or defective mineralization of the skeleton, resulting in soft or fragile bones.

It typically occurs either when there are insufficient amounts of vitamin D in the diet or, more commonly, when the body is unable to properly absorb and metabolize vitamin D, which is essential for the absorption of the calcium needed to maintain strong, healthy bones. It can also occur with calcium and phosphorus deficiency.

When the disease occurs in children, it is known as rickets and tends to produce obvious skeletal deformities. The disease has more subtle manifestations in adults and may be difficult to diagnose or to differentiate from osteoporosis. In some cases repeated pressure on soft bones can lead to fractures or mild deformities.

In adults, when osteomalacia is due to a vitamin D deficiency, treatment usually cures the problem within six months.

MSD and the MSD Veterinary Manual

In children, the disease may be arrested, although skeletal deformities may be permanent. Although common in underdeveloped countries, rickets is now rare in Western nations. What Causes Osteomalacia and Rickets? A chief cause of osteomalacia is intestinal malabsorption of vitamin D.

Osteomalacia may be caused by disorders of any of the organs involved in vitamin D synthesis, such as the skin, kidney and liver. Dietary deficiency of vitamin D is common, especially in the elderly and exclusively breast-fed infants.

Vitamin D is supplied in the diet mainly through vitamin D-fortified dairy products and cereals. However, many adults do not consume enough. Inadequate exposure to sunlight reduces the amount of vitamin D produced naturally by the skin. Chronic renal failure and complications of hemodialysis are potential causes.

Chronic acidosis an abnormal state of reduced alkalinity in the blood or body tissues, usually due to renal failure may lead to osteomalacia. Osteomalacia may occur as a side effect of some anticonvulsant drugs used to treat epilepsy.

An overview of bone diseases

They interfere with normal activation of vitamin D. Several rare hereditary disorders can cause low phosphorus blood levels hypophosphatemiaresulting in osteomalacia. Hypophosphatemia may also result from chronic use of nonabsorbable antacids.

An overview of bone diseases

Symptoms of Osteomalacia and Rickets Bone pain in the arms, legs, spine and especially the hips Muscle weakness, waddling gait Unexplained bone fractures or deformities Painful spasms or cramps in the face, hands and feet due to low levels of calcium in the blood rare In rickets:Spondyloarthritis (pronounced spon-dyl-oh-arthritis) is the name given to a group of closely related rheumatic diseases that primarily affect the spine (spondylo) and other joints.

Spondyloarthritis can sometimes be referend to as spondyloarthropathy, and informally, spondylitis. The term. Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains stem stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting.

Bone disorders in children can result from such causes as injuries, cancer, and infections. Causes of bone disorders that affect mainly children typically involve the gradual misalignment of bones, which is caused by forces exerted on the growth plates as children are developing.

Metabolic bone diseases are disorders of bone strength, usually caused by abnormalities of minerals (such as calcium or phosphorus), vitamin D, bone mass or bone structure.

Primer - American Society for Bone and Mineral Research

The most common metabolic bone disorder is osteoporosis. The bone thickens and osteophytes, or spurs, may form. Spurs protrude from the joint and cause additional problems with movement. Bones begin to rub together, which leads to pain, discomfort, swelling and a change in movement.

Ninth Edition of the Primer is Now Available! Now in its ninth edition, the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health.

Since it was first published 30 years ago, the Primer .

Osteoporosis | MedlinePlus